At this stage it becomes important to remember that science is concerned only with observable things and that we can observe an object only by letting it interact with some outside influence……..The concepts of big and small are then purely relative and refer to the gentleness of our means of observation as well as to the object being described. In order to give an absolute meaning to size, such as is required for any theory of the ultimate structure of matter, we have to assume that there is a limit to the fineness of our powers of observation – a limit which is inherent in the nature of things and can never be surpassed by improved technique or increased skill on the part of the scientist…”
But the Gyān of the Upanishads starts at this point and Brihad-āranyaka Up. III.8.8 says of Brahman , the Ultimate that cannot be known…
He said; ‘That, O Gārgi, the knowers of Brahman, call it the Imperishable. It is neither gross nor fine, neither short nor long, neither glowing red (like fire) nor adhesive (like water), (It is) neither shadow nor darkness, neither air nor space, unattached, without taste, without smell, without eyes, without ears, without voice, without mind, without measure, having no within and no without. It eats nothing and no one eats it. [8]